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JTV1 polyclonal antibody

CAT: 0384-AP6009-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-AP6009-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JTV1, also known as P38 or AIMP2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2), is a 320 amino acid nuclear and cytoplasmic protein that is a component of the aminoacyl-tRNA synthase complex. Containing one GST C-terminal domain, JTV1 mediates ubiquitination and degradation of FBP1, a transcriptional activator of c-Myc, leading to c-Myc down-regulation, which is required for aveolar type II cell differentiation. JTV1 also participates in blocking MDM2-mediated ubiquitination, degradation of p53 and functions as a proapoptotic factor.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; Protein JTV-1; AIMP2; JTV1; PRO0992
Swiss Prot
Q13155
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human JTV1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 35 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
JTV1 polyclonal antibody detects endogenous levels of JTV1 protein.
Host or Source
Rabbit

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