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GFM2 polyclonal antibody

CAT: 0384-BS62364-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62364-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondrial translation is critical for maintaining function and preventing impairment of mitochondrial DNA, with mitochondrial translation elongation factors playing an essential role in this process. EF-G2 (elongation factor G2), also known as RRF2mt (ribosome-releasing factor 2, mitochondrial), GFM2 or MSTP027, is a 779 amino acid protein belonging to the GTP-binding elongation factor family and EF-G/EF-2 subfamily. Localizing to mitochondrion, EF-G2 is widely expressed with high levels found in adult heart, skeletal muscle and kidney as well as adult and fetal liver. EF-G2 mediates ribosome recycling and by interacting directly with MRRF on the ribosome large subunit, is required for ribosome dissociation from mRNA. Existing as five alternatively spliced isoforms, the gene encoding EF-G2 maps to human chromosome 5q13.3.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Ribosome-releasing factor 2, mitochondrial; RRF2mt; Elongation factor G 2, mitochondrial; EF-G2mt; mEF-G 2; Elongation factor G2; hEFG2; GFM2; EFG2; MSTP027
Swiss Prot
Q969S9
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human GFM2.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GFM2 polyclonal antibody detects endogenous levels of GFM2 protein.
Applications Notes
Western blot (WB) analysis of GFM2 polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:PC12 whole cell lysate
Host or Source
Rabbit

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