TLK2 polyclonal antibody

• Background:

  Tousled like kinase 2 (TLK2) Homo sapiens This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Product Name Alternative:

  TLK2; Serine/threonine-protein kinase tousled-like 2; HsHPK; PKU-alpha; Tousled-like kinase 2

• Swiss Prot:

  Q86UE8

• Reactivity:

  Human

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human TLK2. AA range:191-240

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Modification:

  Unmodification

• Molecular Weight:

  ~ 90 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For

• Specificity:

  TLK2 Polyclonal Antibody detects endogenous levels of TLK2 protein.

• Applications Notes:

  Western Blot analysis of various cells using TLK2 Polyclonal Antibody. Secondary antibody (catalog#: RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA) .

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4