IGLL1 polyclonal antibody

• Background :

  Immunoglobulin lambda like polypeptide 1 (IGLL1) Homo sapiens The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Structure Composition :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Product Name Alternative :

  IGLL1; IGL1; Immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD179b

• Swiss Prot :

  P15814

• Reactivity :

  Human

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the C-terminal region of human IGLL1. AA range:151-200

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-p, IF (paraffin section), ELISA

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Modification :

  Unmodification

• Molecular Weight :

  ~ 23 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Lambda 5 Polyclonal Antibody detects endogenous levels of Lambda 5 protein.

• Applications Notes :

  Western Blot analysis of KB cells using Lambda 5 Polyclonal Antibody.. Secondary antibody (catalog#: RS0002) was diluted at 1:20000

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4