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BBS1 Polyclonal Antibody

CAT: 0384-BS65686-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65686-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8 (GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
AI451249; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 1 homolog; Bardet-Biedl syndrome 1 protein; BBS1; BBS1_HUMAN; BBS2-like protein 2; D19Ertd609e.
Swiss Prot
Q8NFJ9
Reactivity
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human BBS5
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB=1:500-2000 IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
65 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BBS1 Polyclonal Antibody detects endogenous levels of BBS1 protein.
Applications Notes
Sample: HepG2 (Human) Cell Lysate at 30 ug U2os (Human) Cell Lysate at 30 ug Primary: Anti- BBS1 at 1/1000 dilution
Host or Source
Rabbit

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