MCT2 polyclonal antibody

• Background :

  Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]) .[supplied by OMIM, Feb 2011].

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  MCT 2; MCT; Monocarboxylate transporter 2; MonocarboxylateTransporter 2; MOT2; MOT2_HUMAN; SLC16A7; Solute carrier family 16 member 7; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7.

• Swiss Prot :

  O70451

• Reactivity :

  Mouse, Rat

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  ~50kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  MCT2 polyclonal Antibody detects endogenous levels of MCT2 protein.

• Applications Notes :

  Anti-MCT2 at 1/1000 dilution

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4