Products for Research Use Only
RegisterLogin

CD63 monoclonal antibody

CAT: 0384-MB66137-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-MB66137-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CD63 belongs to the tetraspanin family, which is characterized by four transmembrane domains, one short extracellular domain (ECL1), and one long extracellular domain (ECL2) . Tetraspanins interact with a variety of cell surface proteins and intracellular signaling molecules in specialized tetraspanin enriched microdomains (TEMs) where they mediate a range of processes including adhesion, motility, membrane organization, and signal transduction . CD63, like other tetraspanins, is enriched in exosomes . It is also a component of Weibel-Palade bodies found in endothelial cells . Research studies demonstrate several functions of CD63 in different cell types including roles in mast cell degranulation, VEGF signaling in endothelial cells, recruitment of leukocytes to endothelial cells, and endosomal sorting during melanogenesis .
CAS Number
9007-83-4
Structure Composition
Mouse IgG2a. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Product Name Alternative
MLA1; TSPAN30; CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63
Swiss Prot
P08962
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within human CD63. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC (1/100 - 1/300)
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of CD63 protein.
Host or Source
Mouse

Related Products

CatalogName
BS72936CD63 polyclonal antibody
NCP0219P-01CD63 polyclonal antibody
BZ16345CD63 polyclonal antibody
BS90254CD63 polyclonal antibody
BS80442-01CD63 polyclonal antibody
PPL00300-1POTB7-CD63
BS3474-01CD63 (K156) polyclonal antibody
NCP0219-01CD63 Recombinant Protein
PPL00300-2bPEGFP-N1-CD63
PPL00300PEASY-T3 CD63

Alternative Products

CatalogName
MBS9018357-01CD63 Monoclonal Antibody
GTR18578535-01CD63 Mouse Monoclonal Antibody
ARO-A15786-01Human CD63 Monoclonal Antibody
AMRe01798-01CD63 Rabbit Monoclonal Antibody
CSB-RA004950A0HU-01CD63 Recombinant Monoclonal Antibody

Popular Products