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CD63 polyclonal antibody

CAT: 0384-BS80442-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS80442-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CD63; LAMP-3; ME491; MLA1; OMA81H; TSPAN30; CD63 antigen; CD63
Swiss Prot
P08962
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CD63 (NP_001771.1) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 30-65 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD63 polyclonal antibody detects endogenous levels of CD63 protein.
Applications Notes
Western blot analysis of CD63 expression in HL-60 (A), RAW264.7 (B), rat brain (C) whole cell lysates.
Host or Source
Rabbit

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