BMP-3 (E306) polyclonal antibody

CAT: 0384-BS3683-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS3683-01Size:50 µL
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Background
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Bone morphogenetic protein 3; BMP-3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin
Swiss Prot
P12645
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human BMP-3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 56 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BMP-3 (E306) polyclonal antibody detects endogenous levels of BMP-3 protein.
Applications Notes
Western blot (WB) analysis of BMP-3 (E306) polyclonal antibody at 1:1000 dilution Lane1:CT26 whole cell lysate (30ug) Lane2:PC12 whole cell lysate (30ug) Lane3:HepG2 whole cell lysate (30ug) Lane4:A549 whole cell lysate (30ug
Host or Source
Rabbit

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