Products for Research Use Only

BMP-5 (L163) polyclonal antibody

CAT: 0384-BS3455-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3455-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis.Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Bone morphogenetic protein 5; BMP-5
Swiss Prot
P22003
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to Human BMP-5.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:2000~1:5000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 53 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BMP-5 (L163) polyclonal antibody detects endogenous levels of BMP-5 protein.
Applications Notes
Western blot (WB) analysis of BMP-5 (L163) polyclonal antibody at 1:2000 dilution Lane1:EC9706 whole cell lysate (30ug) Lane2:HCT116 whole cell lysate (30ug) Lane3:A549 whole cell lysate (30ug) Lane4:HEK293T whole cell lysate (30ug)
Host or Source
Rabbit