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Integrin alpha 5 (ITGA5/CD49e) polyclonal antibody

CAT: 0384-BS78733-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS78733-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CD49e; FNRA; VLA-5; VLA5A; Integrin alpha 5; ITGA5
Swiss Prot
P08648
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human Integrin alpha 5 (ITGA5/CD49e) (NP_002196.4) .
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
135kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

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