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[KO Validated] Integrin alpha 2 (ITGA2/CD49b) polyclonal antibody

CAT: 0384-BS70832-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS70832-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2; ITGA2
Swiss Prot
P17301
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human alpha 2 (ITGA2/CD49b) (NP_002194.2) .
Conjugation
Unconjugated
Applications
WB, IHC-P IF/ICC
Dilution
WB,1:500 - 1:1000|IHC-P,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
150KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Integrin alpha 2 polyclonal antibody detects endogenous levels of Integrin alpha 2 protein.
Host or Source
Rabbit

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