Products for Research Use Only
RegisterLogin

Rb polyclonal antibody

CAT: 0384-BZ16670-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BZ16670-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Swiss Prot
P06400
Reactivity
Human, Rat, Mouse
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RB.
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IHC: 1/100-1/200 IF/ICC: 1/100-1/500 IP: 1/10-1/50
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Rb polyclonal antibody detects endogenous levels of Rb protein.
Applications Notes
Western blot analysis of Rb expression in PC3 (A), Hela (B), NIH3T3 (C) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS3737-01Rb (T601) polyclonal antibody
BS1311Rb (P789) polyclonal antibody
BS1792-01Rb (S807) polyclonal antibody
BZ17056-01Phospho-Rb (Ser807) polyclonal antibody
BS6414-01Phospho-RB-S795 polyclonal antibody
BS4164-01Rb (phospho-S780) polyclonal antibody
BS6415-01Phospho-RB-S811 polyclonal antibody
BS79404-01Phospho-RB-S608 polyclonal antibody
BS79479-01Phospho-RB-S795 polyclonal antibody
BZ16380-01Phospho-Rb (Ser780) polyclonal antibody

Alternative Products

CatalogName
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody
APR00451GPolyclonal SPI1 polyclonal antibody
APR00373GPolyclonal EzH2 polyclonal antibody
APR14018GPolyclonal YY1 polyclonal antibody
PTX18700-100UCN3 Polyclonal Polyclonal Antibody
PTX18688-100TKT Polyclonal Polyclonal Antibody
PTX18684-100TGFA Polyclonal Polyclonal Antibody
PTX18678-100SYT1 Polyclonal Polyclonal Antibody

Popular Products