MDM2 polyclonal antibody

• Background :

  E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.

• Structure Composition :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative :

  Double minute 2 protein; Hdm2; Oncoprotein Mdm2

• Swiss Prot :

  Q00987

• Reactivity :

  Human, Rat

• Immunogen :

  Synthetic peptide of human MDM2

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-P, ICC/IF

• Dilution :

  WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 55 kDa; Observed MW: 90 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of MDM2 in SKOV-3 lysates using MDM2 antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4