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TLX agonist 1

CAT: 0804-HY-135572-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135572-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM) . TLX agonist 1 potentiates TLX transcriptional repressive activity[1].
CAS Number
958323-31-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Orphan Nuclear Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tlx-agonist-1.html
Purity
99.92
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(C1=NN(C)C(C)=C1)N2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2
Molecular Formula
C23H26N4O
Molecular Weight
374.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Benod C, et al. The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable. PLoS One. 2014 Jun 17;9 (6) :e99440.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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