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Tilmicosin-d3

CAT: 0804-HY-B0905SSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0905SSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects[1][2].
CAS Number
2714486-61-8
Product Name Alternative
LY-177370-d3; EL-870-d3
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H334, H335, H410
Target
Antibiotic; Apoptosis; Bacterial; COX; Isotope-Labeled Compounds; NO Synthase
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Others
Field of Research
Infection; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
C[C@@H]([C@@H](CC1=O)O)[C@H]([C@H](C[C@H](C(/C=C/C(C)=C/[C@H](CO[C@H](O[C@H](C)[C@@H](O)[C@H]2OC)[C@@H]2OC)[C@@H](CC)O1)=O)C)CCN(C[C@H](C)C3)C[C@H]3C)O[C@@](O[C@H](C)[C@@H](O)[C@@H]4N(C)C([2H])([2H])[2H])([H])[C@@H]4O
Molecular Formula
C46H77D3N2O13
Molecular Weight
872.15
Precautions
H315, H317, H319, H334, H335, H410
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Micotil 300 New Animal Drug Application
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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