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Atropine-d5

CAT: 0804-HY-B0394SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0394SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atropine-d5 is the deuterium labeled Atropine (sulfate monohydrate) . Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect[1].
Product Name Alternative
Tropine tropate-d5; DL-Hyoscyamine-d5
UNSPSC
12352005
Target
Autophagy; mAChR
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Purity
99.0
Solubility
10 mM in DMSO
Smiles
OCC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])C(O[C@@H]2C[C@@H]3N([C@@H](CC3)C2)C)=O
Molecular Formula
C17H18D5NO3
Molecular Weight
294.40
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]McBrien NA, et al. How does atropine exert its anti-myopia effects? Ophthalmic Physiol Opt. 2013 May;33 (3) :373-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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