Atropine-d5

• Description:

  Atropine-d5 is the deuterium labeled Atropine (sulfate monohydrate) . Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect[1].

• Product Name Alternative:

  Tropine tropate-d5; DL-Hyoscyamine-d5

• UNSPSC:

  12352005

• Target:

  Autophagy; mAChR

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Autophagy; GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Purity:

  99.0

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])C(O[C@@H]2C[C@@H]3N([C@@H](CC3)C2)C)=O

• Molecular Formula:

  C17H18D5NO3

• Molecular Weight:

  294.40

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]McBrien NA, et al. How does atropine exert its anti-myopia effects? Ophthalmic Physiol Opt. 2013 May;33 (3) :373-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported