Products for Research Use Only
RegisterLogin

Atropine

CAT: 0804-HY-B1205-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1205-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia[1][2][3][4].
CAS Number
51-55-8
Product Name Alternative
Tropine tropate; DL-Hyoscyamine
UNSPSC
12352005
Hazard Statement
H300, H330
Target
Endogenous Metabolite; mAChR
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Atropine.html
Purity
99.85
Solubility
DMSO : ≥ 96.6 mg/mL|H2O : 2.9 mg/mL (ultrasonic; warming)
Smiles
O=C(O[C@@H]1C[C@@H](N2C)CC[C@@H]2C1)C(CO)C3=CC=CC=C3
Molecular Formula
C17H23NO3
Molecular Weight
289.38
Precautions
H300, H330
References & Citations
[1]McBrien NA, et, al. How does atropine exert its anti-myopia effects? Ophthalmic Physiol Opt. 2013 May;33 (3) :373-8.|[2]Morhardt JE. Heart rates, breathing rates and the effects of atropine and acetylcholine on white-footed mice (Peromyscus sp.) during daily torpor. Comp Biochem Physiol. 1970 Mar 15;33 (2) :441-57.|[3]Carr BJ, et, al. Myopia-Inhibiting Concentrations of Muscarinic Receptor Antagonists Block Activation of Alpha2A-Adrenoceptors In Vitro. Invest Ophthalmol Vis Sci. 2018 Jun 1;59 (7) :2778-2791.|[4]Walch L, et, al. Evidence for a M (1) muscarinic receptor on the endothelium of human pulmonary veins. Br J Pharmacol. 2000 May;130 (1) :73-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
MAChR4
Citation 01
Can J Physiol Pharmacol. 2020 Oct;98 (10) :725-732.|Cardiovasc Drugs Ther. 2025 Apr 7.|Cell Metab. 2022 Dec 6;34 (12) :1999-2017.e10.|Cell Rep. 2022 Mar 8;38 (10) :110468.|Cell. 2025 Oct 24:S0092-8674 (25) 01129-8.|Eur J Pharmacol. 2024 Sep 3:176954.|Food Chem. 2022 Nov 30:395:133593.|Front Pharmacol. 2020 Jul 31;11:1038.|J Biosci. 2021:46:90.|J Ethnopharmacol. 2024 Jan 30;319 (Pt 2) :117192.|J Hazard Mater. 2024 Mar 5:465:133248.|J Hazard Mater. 2024 Sep 5:479:135690.|J Transl Med. 2025 Jan 23;23 (1) :112.|Research Square Preprint. 2022 Mar.|Research Square Print. 2023 Feb 7.|Research Square Print. December 16th, 2022.|Arch Oral Biol. 2023 Jan:145:105586.|Cell Discov. 2023 Feb 7;9 (1) :16.|Neuron. 2022 Nov 16;110 (22) :3774-3788.e7.

Related Products

CatalogName
HY-N7091-01Atrazine
HY-N7091S-01Atrazine-15N
HY-N7091S2-01Atrazine-d5
HY-126816-01Atrazine mercapturate
HY-N7091R-01Atrazine (Standard)
HY-132394S-01Hydroxy Atrazine-d5
HY-W704138-012-Hydroxy-atrazine
HY-N7091S1Atrazine-13C3,15N3
HY-163023Atrazine-acetic acid
HY-W704138R2-Hydroxy-atrazine (Standard)

Alternative Products

CatalogName
FA32433-01Atropine
CS-T-95209Atropine-d5
AB2512Atropine Sulfat
MBS3605014-01Atropine sulfate
OR1037239A-Hydroxymethyl atropine
TRC-A794632-1MG(±)-Atropine-D3

Popular Products