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Meloxicam (sodium)

CAT: 0804-HY-B0261ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0261ASize:1 Each
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Description
Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively[1].
CAS Number
71125-39-8
UNSPSC
12352005
Hazard Statement
H301-H315-H319-H335
Target
Apoptosis; Autophagy; COX; MMP
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/meloxicam-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O[Na])C2=CC=CC=C2S(N1C)(=O)=O)NC3=NC=C(C)S3
Molecular Formula
C14H12N3NaO4S2
Molecular Weight
373.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40 (6) :980-9.|[2]Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14 (2) :2198-2206.|[3]Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32 (2) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
COX-1; COX-2; MMP-2

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