(-) -Ketoconazole-d3

• Description :

  (-) -Ketoconazole-d3 is deuterium labeled (-) -Ketoconazole. (-) -Ketoconazole ((-) -R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R) - (−) -ketoconazole) and dextroketoconazole ((2R,4S) - (+) -ketoconazole) .

• CAS Number :

  [1217766-70-5]

• Product Name Alternative :

  (-) -Ketoconazol-d3; (-) -R 41400-d3

• UNSPSC :

  12352005

• Hazard Statement :

  H301-H360-H373-H400-H410

• Target :

  Fungal; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Solubility :

  10 mM in DMSO

• Smiles :

  [2H]C([2H])([2H])C(N(CC1)CCN1C(C=C2)=CC=C2OC[C@H](CO3)O[C@@]3(C4=C(C=C(C=C4)Cl)Cl)CN5C=CN=C5)=O

• Molecular Formula :

  C26H25D3Cl2N4O4

• Molecular Weight :

  534.45

• Precautions :

  P260-P264-P270-P273-P280-P330-P391-P405-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported