(-) -Ketoconazole

• Description:

  (-) -Ketoconazole ((-) -R 41400) is one of the enantiomers of ketoconazole (HY-B0105) . Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R) - (−) -ketoconazole) and dextroketoconazole ((2R,4S) - (+) -ketoconazole) . Ketoconazole is an antifungal agent and a cytochrome P450 inhibitor.

• Product Name Alternative:

  (-) -Ketoconazol; (-) -R 41400

• UNSPSC:

  12352005

• Target:

  Cytochrome P450; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/_-_-Ketoconazole.html

• Purity:

  99.71

• Solubility:

  DMSO : 33.33 mg/mL (ultrasonic)

• Smiles:

  CC(N1CCN(C2=CC=C(OC[C@H]3O[C@](CN4C=CN=C4)(C5=CC=C(Cl)C=C5Cl)OC3)C=C2)CC1)=O

• Molecular Formula:

  C26H28Cl2N4O4

• Molecular Weight:

  531.43

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [142128-57-2]