Ispinesib-d5

• Description :

  Ispinesib-d5 (SB-715992-d5) is a deuterium labeled Ispinesib (HY-50759) . Ispinesib is a specific inhibitor of kinesin spindle protein (KSP) [1].

• Product Name Alternative :

  SB-715992-d5

• UNSPSC :

  12352005

• Target :

  Apoptosis; Kinesin

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(CC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C([C@@H](C(C)C)N(CCCN)C(C3=CC=C(C)C=C3)=O)=NC4=CC(Cl)=CC=C14

• Molecular Formula :

  C30H28D5ClN4O2

• Molecular Weight :

  522.09

• References & Citations :

  [1]Purcell JW, et al. Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer. Clin Cancer Res. 2010 Jan 15;16 (2) :566-76.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported