MC-Val-Cit-PAB-Ispinesib

• UNSPSC Description:

  MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib is a click chemistry reagent[1].

• Target Antigen:

  Kinesin

• Type:

  ADC Related

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mc-val-cit-pab-ispinesib.html

• Solubility:

  Chloroform : ≥ 100 mg/mL

• Smiles:

  O=C(C1=CC=C(C=C1)C)N(CCCNC(OCC2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)[C@@H](C(N4CC5=CC=CC=C5)=NC6=CC(Cl)=CC=C6C4=O)C(C)C

• Molecular Weight:

  1115.71

• References & Citations:

  [1]Paul A. Barsanti, et al. Cell proliferation inhibitors and conjugates thereof. WO2014151030. 2014-09-25

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  Phase 3

• CAS Number:

  1629737-40-1