MC-Val-Cit-PAB-Ispinesib

MC-Val-Cit-PAB-Ispinesib

• CAS Number: 1629737-40-1
• UNSPSC Description: MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib is a click chemistry reagent[1].
• Target Antigen: Kinesin
• Type: ADC Related
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mc-val-cit-pab-ispinesib.html
• Solubility: Chloroform : ≥ 100 mg/mL
• Smiles: O=C(C1=CC=C(C=C1)C)N(CCCNC(OCC2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)[C@@H](C(N4CC5=CC=CC=C5)=NC6=CC(Cl)=CC=C6C4=O)C(C)C
• Molecular Weight: 1115.71
• References & Citations: [1]Paul A. Barsanti, et al. Cell proliferation inhibitors and conjugates thereof. WO2014151030. 2014-09-25
• Shipping Conditions: Blue Ice
• Clinical Information: Phase 3