Valacyclovir (hydrochloride hydrate)

Valacyclovir (hydrochloride hydrate)

• CAS Number: 1218948-84-5
• UNSPSC Description: Valacyclovir hydrochloride hydrate is a potent antiviral agent. Valacyclovir hydrochloride hydrate can be used in the management of herpes simplex, herpes zoster and herpes B. Valacyclovir hydrochloride hydrate can be formulate ocular inserts for the research of ocular herpes. Valacyclovir hydrochloride hydrate is a precursor and can be rapidly converted into acyclovir in vivo[1][2].
• Target Antigen: Bacterial; HSV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/valacyclovir-hydrochloride-hydrate.html
• Solubility: 10 mM in DMSO
• Smiles: N[C@@H](C(C)C)C(OCCOCN1C=NC2=C1N=C(N)NC2=O)=O.[H]Cl.O.[x]
• References & Citations: [1]Zhang Y,et al. Acute renal injury induced by valacyclovir hydrochloride: A case report. Exp Ther Med. 2016 Dec;12(6):4025-4028.|[2]Shadambikar G, et al. Novel Application of Hot Melt Extrusion Technology for Preparation and Evaluation of Valacyclovir Hydrochloride Ocular Inserts. AAPS PharmSciTech. 2021 Jan 14;22(1):48.
• Shipping Conditions: Room temperature
• Clinical Information: Launched