Valacyclovir-d8 (hydrochloride)

CAT: 0804-HY-17425AS-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-17425AS-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Valacyclovir-d8 (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml) . Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) [1][2][3][4][5].
CAS Number
[1279033-32-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Antibiotic; HSV
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Field of Research
Infection
Purity
98.0
Solubility
10 mM in DMSO|DMF : ≥ 10mg/mL|DMSO : ≥ 3mg/mL
Smiles
NC(C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])([2H])C(OCCOCN1C=NC2=C1N=C(N)NC2=O)=O.Cl
Molecular Formula
C13H13D8ClN6O4
Molecular Weight
368.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Valacyclovir. New indication: for genital herpes, simpler administration. Can Fam Physician. 1999 Jul;45:1698-700, 1703-5.|[3]Lycke J, et al. Acyclovir levels in serum and cerebrospinal fluid after oral administration of valacyclovir. Antimicrob Agents Chemother. 2003 Aug;47 (8) :2438-41.|[4]Comparison of efficacies of famciclovir and valaciclovir against herpes simplex virus type 1 in a murineimmunosuppression model. Antimicrob Agents Chemother. 1995 May;39 (5) :1114-9.|[5]Dhaliwal DK, Romanowski EG, Yates KA, Valacyclovir inhibits recovery of ocular HSV-1 after experimental reactivation by excimer laser keratectomy. Cornea. 1999 Nov;18 (6) :693-9.|[6]Guo A, Hu P, Balimane PV, Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.J Pharmacol Exp Ther. 1999 Apr;289 (1) :448-54.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-17425A-01Valacyclovir (hydrochloride)
HY-17425AS1-01Valacyclovir-d4 (hydrochloride)
HY-17425BValacyclovir (hydrochloride hydrate)
HY-17425AR-01Valacyclovir (hydrochloride) (Standard)
HY-B0098BS-01Doxazosin-d8 (hydrochloride)
HY-B0268S1Enoxacin-d8 (hydrochloride)
HY-B1776ASSpermidine-d8 (hydrochloride)
HY-B0126ASMarbofloxacin-d8 (hydrochloride)
HY-17390BS-01Loxapine-d8 (hydrochloride)
HY-B1115SBuspirone-d8 (hydrochloride)

Alternative Products

CatalogName
sc-475557L-Valacyclovir-d8 Hydrochloride
V085001Valacyclovir-d8 Hydrochloride (L-valine-d8)
BUP15676-01Valacyclovir hydrochloride
TRC-V085002-10MGValacyclovir-d4, Hydrochloride
TRC-V085000-50MGL-Valacyclovir Hydrochloride
MBS6043104-01D-Valacyclovir Hydrochloride
2201-50Valacyclovir Hydrochloride Hydrate
459642N-t-Boc-valacyclovir-d8

Popular Products