Products for Research Use Only
RegisterLogin

Valacyclovir-d4 (hydrochloride)

CAT: 0804-HY-17425AS1-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-17425AS1-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Valacyclovir-d4 (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir[2][3][4][5].
CAS Number
1331910-75-8
UNSPSC
12352005
Target
Antibiotic; HSV; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
C(OC(C(OC([C@H](C(C)C)N)=O)([2H])[2H])([2H])[2H])N1C2=C(N=C1)C(=O)N=C(N)N2.Cl
Molecular Formula
C13H17D4ClN6O4
Molecular Weight
364.82
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Valacyclovir. New indication: for genital herpes, simpler administration. Can Fam Physician. 1999 Jul;45:1698-700, 1703-5.|[3]Lycke J, et al. Acyclovir levels in serum and cerebrospinal fluid after oral administration of valacyclovir. Antimicrob Agents Chemother. 2003 Aug;47 (8) :2438-41.|[4]Comparison of efficacies of famciclovir and valaciclovir against herpes simplex virus type 1 in a murineimmunosuppression model. Antimicrob Agents Chemother. 1995 May;39 (5) :1114-9.|[5]Dhaliwal DK, Romanowski EG, Yates KA, Valacyclovir inhibits recovery of ocular HSV-1 after experimental reactivation by excimer laser keratectomy. Cornea. 1999 Nov;18 (6) :693-9.|[6]Guo A, Hu P, Balimane PV, Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.J Pharmacol Exp Ther. 1999 Apr;289 (1) :448-54.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-17425A-01Valacyclovir (hydrochloride)
HY-17425AR-01Valacyclovir (hydrochloride) (Standard)
HY-17425BValacyclovir (hydrochloride hydrate)
HY-17425AS-01Valacyclovir-d8 (hydrochloride)
HY-132702S-01N-t-Boc-valacyclovir-d4
HY-17425-01Valacyclovir
HY-10019AS1Varenicline-d4 (hydrochloride)
HY-W704876Procaine (hydrochloride) -d4
HY-B1339SDicyclomine-d4 (hydrochloride)
HY-B0352S3Mirtazapine-d4 (hydrochloride)

Alternative Products

CatalogName
CS-O-02873Valacyclovir-d4 Hydrochloride
TRC-V085002-1MGValacyclovir-d4, Hydrochloride
BUP15676-01Valacyclovir hydrochloride
TRC-V085000-5GL-Valacyclovir Hydrochloride
AR-V06019-01Valacyclovir Hydrochloride Dihydrate
291885-01D-Valacyclovir hydrochloride
2201-50Valacyclovir Hydrochloride Hydrate

Popular Products