Abacavir-d4
CAT:
804-HY-17423S
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Abacavir-d4
- CAS Number: 1260619-56-4
- UNSPSC Description: Abacavir-d4 is the deuterium labeled Abacavir. Abacavir is a potent nucleoside analog reverse-transcriptase inhibitor (NRTI)[1][2].
- Target Antigen: Apoptosis; HIV; Isotope-Labeled Compounds; Reverse Transcriptase
- Type: Isotope-Labeled Compounds
- Related Pathways: Anti-infection;Apoptosis;Others
- Field of Research: Infection
- Solubility: 10 mM in DMSO
- Smiles: OC[C@@H]1C=C[C@H](N2C=NC3=C(NC4C([2H])([2H])C4([2H])[2H])N=C(N)N=C23)C1
- Molecular Weight: 290.36
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Charneira C, et al. Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity. Chem Res Toxicol. 2011 Dec 19;24(12):2129-41.|[3]Hervey PS, et al. Abacavir: a review of its clinical potential in patients with HIV infection. Drugs. 2000 Aug;60(2):447-79.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported