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Oseltamivir-d5 (phosphate)

CAT: 0804-HY-17016SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17016SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oseltamivir-d5 (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].
Product Name Alternative
GS 4104-d5 (phosphate)
UNSPSC
12352211
Target
Influenza Virus; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
N[C@H]1CC(C(OC(C([2H])([2H])[2H])([2H])[2H])=O)=C[C@H]([C@@H]1NC(C)=O)OC(CC)CC.O=P(O)(O)O
Molecular Formula
C16H26D5N2O8P
Molecular Weight
415.43
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]de Oliveira JT, et al. Anti-influenza neuraminidase inhibitor Oseltamivir phosphate induces canine mammary cancer cell aggressiveness. PLoS One. 2015 Apr 7;10 (4) :e0121590.|[3]Huang H, et al. Transplacental transfer of Oseltamivir phosphate and its metabolite Oseltamivir carboxylate using the ex vivo human placenta perfusion model in Chinese Hans population. J Matern Fetal Neonatal Med. 2016 Aug 8:1-5.|[4]Li P, et al. A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Gaussia Luciferase. Viruses. 2018 Jun 13;10 (6) . pii: E325.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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