Oseltamivir-d3 (phosphate)

Oseltamivir-d3 (phosphate)

• UNSPSC Description: Oseltamivir-d3 (phosphate)eis the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
• Target Antigen: Influenza Virus; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Others
• Field of Research: Infection
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C([2H])([2H])[2H])=O)[C@@H](N)C1)OCC.O=P(O)(O)O
• Molecular Weight: 413.42
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Huang H, et al. Transplacental transfer of Oseltamivir phosphate and its metabolite Oseltamivir carboxylate using the ex vivo human placenta perfusion model in Chinese Hans population. J Matern Fetal Neonatal Med. 2016 Aug 8:1-5.|[3]de Oliveira JT, et al. Anti-influenza neuraminidase inhibitor Oseltamivir phosphate induces canine mammary cancer cell aggressiveness. PLoS One. 2015 Apr 7;10(4):e0121590.|[4]Li P, et al. A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Gaussia Luciferase. Viruses. 2018 Jun 13;10(6). pii: E325.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported