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Oseltamivir . phosphate

CAT: 0223-10-036Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0223-10-036Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. It is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir carboxylate, it can competitively inhibit viral neuraminidase (IC50s=0.1-4.9nM for influenza neuraminidases A and B) . The enzyme cleaves the sialic acid which is found on glycoproteins on the surface of human cells that helps new virions to exit the cell. Thus oseltamivir is blocking the release of new viral particles from a host cell. Oseltamivir phosphate is used clinically to treat influenza A and influenza B and to prevent flu after exposure. It potentially could be used to reduce the spread of the SARS-CoV-2 and counteract against the transmission of COVID-19
CAS Number
204255-11-8
Type
Chemical
Purity
Greater than or equal to 98% (HPLC)
Shipping Conditions
Room Temp
Storage Conditions
Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
Calculated Molecular Weight
312.4 . 98.0
Other Product Names
GS-4104; Ro 64-0796/002; Tamiflu
Physical Properties
Lyophilized

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