SARS-CoV-2 Mpro-IN-14

SARS-CoV-2 Mpro-IN-14

• CAS Number: 2679814-93-6
• UNSPSC Description: SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-mpro-in-14.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(N(C)C=C1C(C=C2C3=CC(OCC4=C(Cl)C=CC=C4)=C(F)C(Cl)=C3)=CN(C5=CC=CN=C5)C2=O)=O
• Molecular Weight: 565.38
• References & Citations: [1]Zhang CH, et al. Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 2021 Jul 14;12(8):1325-1332.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported