SARS-CoV-2 Mpro-IN-14

• UNSPSC Description:

  SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-2-mpro-in-14.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC(N(C)C=C1C(C=C2C3=CC(OCC4=C(Cl)C=CC=C4)=C(F)C(Cl)=C3)=CN(C5=CC=CN=C5)C2=O)=O

• Molecular Weight:

  565.38

• References & Citations:

  [1]Zhang CH, et al. Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 2021 Jul 14;12(8):1325-1332.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2679814-93-6