SARS-CoV-2 Mpro-IN-7

• UNSPSC Description:

  SARS-CoV-2 Mpro-IN-7 (compound 6g) is a potent inhibitor of Mpro-SARS-CoV-2 (IC50=8.8 μM, CC50=10 μM)[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-2-mpro-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@@]2([C@]3(C(C=CC=C4)=C4NC3=O)N(C)C[C@]2(C5=CC=C(Br)C=C5)[H])CN(P(OCC)(OCC)=O)C/C1=C\C6=CC=C(Br)C=C6

• Molecular Weight:

  743.42

• References & Citations:

  [1]Bekheit MS, et al. Spiroindole-containing compounds bearing phosphonate group of potential Mpro-SARS-CoV-2 inhibitory properties. Eur J Med Chem. 2023 Oct 5;258:115563.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported