SARS-CoV MPro-IN-2

SARS-CoV MPro-IN-2

• CAS Number: 81418-42-0
• UNSPSC Description: SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in agent discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19[1].
• Target Antigen: SARS-CoV
• Type: Natural Products
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-mpro-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(C(C)=O)=CC(C2=C1C(OC)=CC=C2)=O
• Molecular Weight: 230.22
• References & Citations: [1] Cui J, et al. Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors. Eur J Med Chem. 2021;225:113789.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported