Anticancer agent 180

• Description:

  Anticancer agent 180 (compound 4) is a secondary metabolite induced by co-culture of fungi and actinomycetes, the later one can produce HDAC inhibitors Trichostatins. Anticancer agent 180 has potential anti-tumor activity and can inhibit the migration of MDA-MB-231 breast cancer cells[1].

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-180.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C(C1=CC=C(C=C1)O)=CN(C)C2=O)=C2[C@@]3([H])O[C@](CCC(CC(CC)C)C)([H])CCC3

• Molecular Formula:

  C26H37NO4

• Molecular Weight:

  427.58

• References & Citations:

  [1]Hwang GJ, et al. Induction of Fungal Secondary Metabolites by Co-Culture with Actinomycete Producing HDAC Inhibitor Trichostatins. J Microbiol Biotechnol. 2023 Nov 28;33 (11) :1437-1447.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [9007-83-4]