Antitubercular agent-43

• UNSPSC Description:

  Antitubercular agent-43 (compound A11) is an orally active and potent antitubercular agent. Antitubercular agent-43 shows highly metabolic stability against human and mouse cytochrome P450 enzymes. Antitubercular agent-43 exhibits bactericidal efficacy in acute TB infection mouse model[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antitubercular-agent-43.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN(C1=NC(C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2S1)=O)CC#CC3=CSC=N3

• Molecular Weight:

  426.39

• References & Citations:

  [1]Wu X, et al. Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation. Eur J Med Chem. 2023 Nov 25;264:115976.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4