Antitubercular agent-16

• UNSPSC Description:

  Antitubercular agent-16 (Compound 5q) is an antitubercular agent with MIC90 values of 0.40, 20.11, 23.51, 19.62, 10.93 and 13.62 μg/mL against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161, respectively. Antitubercular agent-16 shows low cytotoxicity against macrophages and pulmonary fibroblasts[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antitubercular-agent-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC(CNCC2CCCCC2)=C(N1C3=NC4=C(S3)C=CC=C4)C

• Molecular Weight:

  353.52

• References & Citations:

  [1]Semenya D, et al. Tapping into the antitubercular potential of 2,5-dimethylpyrroles: A structure-activity relationship interrogation. Eur J Med Chem. 2022 Jul 5;237:114404.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4