Antitubercular agent-28

• UNSPSC Description:

  Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 μM, an MIC value of 4.5 μM, an IC90 value of 2.5 μM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antitubercular-agent-28.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NN1C(C2CC2)=NC3=C(C=CC=C3)C1=O)C4=CC=NC=C4

• Molecular Weight:

  306.32

• References & Citations:

  [1]Patel H, et al. Synthesis and in vitro antitubercular activity of pyridine analouges against the resistant Mycobacterium tuberculosis. Bioorg Chem. 2020 Sep;102:104099.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4