Antitubercular agent-28

• Description :

  Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 μM, an MIC value of 4.5 μM, an IC90 value of 2.5 μM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antitubercular-agent-28.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NN1C(C2CC2)=NC3=C(C=CC=C3)C1=O)C4=CC=NC=C4

• Molecular Formula :

  C17H14N4O2

• Molecular Weight :

  306.32

• References & Citations :

  [1]Patel H, et al. Synthesis and in vitro antitubercular activity of pyridine analouges against the resistant Mycobacterium tuberculosis. Bioorg Chem. 2020 Sep;102:104099.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2460651-10-7]