Antitubercular agent-35

• Description :

  Antitubercular agent-35 (compound 42l) is an antitubercular agent. Antitubercular agent-35 inhibits the growth of MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively. Antitubercular agent-35 shows the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent-35 can be used for the research of tuberculosis[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antitubercular-agent-35.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=NOC(C2=CSC(NC3=CC=C(C=C3)Cl)=N2)=C1)NC4=CC=CC=C4

• Molecular Formula :

  C19H13ClN4O2S

• Molecular Weight :

  396.85

• References & Citations :

  [1]Girardini M, et al. Expanding the knowledge around antitubercular 5- (2-aminothiazol-4-yl) isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114916.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [9007-83-4]