PARP1-IN-18

PARP1-IN-18

• CAS Number: 2958609-64-6
• UNSPSC Description: PARP1-IN-18 (compound 25) is a potent PARP1 inhibitor with an IC50 value of 2.7 nM. PARP1-IN-18 has anticancer effects[1].
• Target Antigen: PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/parp1-in-18.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1CC1)C2=CC=C(N3CCN(CC4=CC=C(C=C(C(F)F)C(N5)=O)C5=C4F)CC3)C(F)=N2
• Molecular Weight: 489.47
• References & Citations: [1]Sabnis RW. Novel Azaquinolones as PARP1 Inhibitors for Treating Cancer. ACS Med Chem Lett. 2021 Mar 16;12(4):524-525.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported