Anticancer agent 178

Anticancer agent 178

• CAS Number: 9007-83-4
• UNSPSC Description: Anticancer agent 178 (compound C2) is a potent anticancer agent. Anticancer agent 178 inhibits MDA-MB 231 cells proliferation and metabolic activity with IC50s of 1.1 and 4.2 μM. Anticancer agent 178 induces ferroptosis and necroptosis in cells[1].
• Target Antigen: Ferroptosis; Necroptosis
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/anticancer-agent-178.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(C2C(C3=CC=C(OC)C=C3)[N]4=CC5=C(C=C(OC)C=C5)O[Fe]46(Cl)[N]2=CC7=CC=C(OC)C=C7O6)C=C1
• Molecular Weight: 629.89
• References & Citations: [1]Bernkop-Schnürch A D, et al. Design, Synthesis, Electrochemical, and Biological Evaluation of Fluorescent Chlorido [N, N′-bis (methoxy/hydroxy) salicylidene-1, 2-bis (4-methoxyphenyl) ethylenediamine] iron (III) Complexes as Anticancer Agents[J]. Journal of Medicinal Chemistry, 2023.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported