Anticancer agent 178

• Description :

  Anticancer agent 178 (compound C2) is a potent anticancer agent. Anticancer agent 178 inhibits MDA-MB 231 cells proliferation and metabolic activity with IC50s of 1.1 and 4.2 μM. Anticancer agent 178 induces ferroptosis and necroptosis in cells[1].

• UNSPSC :

  12352005

• Target :

  Ferroptosis; Necroptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-178.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=CC=C(C2C(C3=CC=C(OC)C=C3)[N]4=CC5=C(C=C(OC)C=C5)O[Fe]46(Cl)[N]2=CC7=CC=C(OC)C=C7O6)C=C1

• Molecular Formula :

  C32H30ClFeN2O6

• Molecular Weight :

  629.89

• References & Citations :

  [1]Bernkop-Schnürch A D, et al. Design, Synthesis, Electrochemical, and Biological Evaluation of Fluorescent Chlorido [N, N′-bis (methoxy/hydroxy) salicylidene-1, 2-bis (4-methoxyphenyl) ethylenediamine] iron (III) Complexes as Anticancer Agents[J]. Journal of Medicinal Chemistry, 2023.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [9007-83-4]