Anticancer agent 178

CAT: 0804-HY-162046Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162046Size:1 Each
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Description
Anticancer agent 178 (compound C2) is a potent anticancer agent. Anticancer agent 178 inhibits MDA-MB 231 cells proliferation and metabolic activity with IC50s of 1.1 and 4.2 μM. Anticancer agent 178 induces ferroptosis and necroptosis in cells[1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Ferroptosis; Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-178.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C2C(C3=CC=C(OC)C=C3)[N]4=CC5=C(C=C(OC)C=C5)O[Fe]46(Cl)[N]2=CC7=CC=C(OC)C=C7O6)C=C1
Molecular Formula
C32H30ClFeN2O6
Molecular Weight
629.89
References & Citations
[1]Bernkop-Schnürch A D, et al. Design, Synthesis, Electrochemical, and Biological Evaluation of Fluorescent Chlorido [N, N′-bis (methoxy/hydroxy) salicylidene-1, 2-bis (4-methoxyphenyl) ethylenediamine] iron (III) Complexes as Anticancer Agents[J]. Journal of Medicinal Chemistry, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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