Anticancer agent 178

• Description:

  Anticancer agent 178 (compound C2) is a potent anticancer agent. Anticancer agent 178 inhibits MDA-MB 231 cells proliferation and metabolic activity with IC50s of 1.1 and 4.2 μM. Anticancer agent 178 induces ferroptosis and necroptosis in cells[1].

• UNSPSC:

  12352005

• Target:

  Ferroptosis; Necroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-178.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC=C (C2C (C3=CC=C (OC) C=C3) [N]4=CC5=C (C=C (OC) C=C5) O[Fe]46 (Cl) [N]2=CC7=CC=C (OC) C=C7O6) C=C1

• Molecular Formula:

  C32H30ClFeN2O6

• Molecular Weight:

  629.89

• References & Citations:

  [1]Bernkop-Schnürch A D, et al. Design, Synthesis, Electrochemical, and Biological Evaluation of Fluorescent Chlorido [N, N′-bis (methoxy/hydroxy) salicylidene-1, 2-bis (4-methoxyphenyl) ethylenediamine] iron (III) Complexes as Anticancer Agents[J]. Journal of Medicinal Chemistry, 2023.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4