ARQ-736

• Description :

  ARQ-736 is a potent and selective B-RAF inhibitor that plays an important role in cancer study[1].

• UNSPSC :

  12352005

• Target :

  Raf

• Type :

  Reference compound

• Related Pathways :

  MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/arq-736.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=P(O[Na])(O[Na])OCOC1=CC=CC(C(N=C2N3C=CO2)=C3C4=NC(N[C@H]5CN(CCC5)S(=O)(C6=NN(C)C=C6)=O)=NC=C4)=C1

• Molecular Formula :

  C25H25N8Na2O8PS

• Molecular Weight :

  674.53

• References & Citations :

  [1]Tiangui Huang, et al. B-Raf and the inhibitors: from bench to bedside. J Hematol Oncol. 2013 Apr 25:6:30.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  B-Raf

• CAS Number :

  [1228237-57-7]