TNF-alpha-IN-1

TNF-alpha-IN-1

• UNSPSC Description: TNF-alpha-IN-1 (compound 202) is an orally active inhibitor of TNF-alpha. TNF-alpha-IN-1 has anti-inflammatory activity which can used in study rheumatoid arthritis, psoriasis, and asthma[1].
• Target Antigen: TNF Receptor
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/tnf-alpha-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@@H](NC([C@H](NC(CCC(NC1=CC=C(C[C@H](N2)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)C=C1)=O)=O)CCC4=CC=CC=C4)=O)CC5=CC=C(C6=CC=CC=C6)C=C5)C[C@H](CC7=CC=CC=C7)C2=O
• Molecular Weight: 940.09
• References & Citations: [1]Jinbo Lee, et al. Macrocyclic compounds for inhibition of tumor necrosis factor alpha. United States, US8338565B2. 2012-12-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported