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BTK-IN-28

CAT: 0804-HY-157159Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157159Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-28 (compound PID-4) is a potent BTK inhibitor with anticancer activity. BTK-IN-28 has inhibitory effects on BTK and downstream signaling cascades and selectively inhibits Burkitt lymphoma RAMOS proliferation. BTK-IN-28 has no significant cytotoxicity towards non-tumor cells[1].
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-28.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC2=C(NC(/C2=C3CCOCC\3)=O)C=C1)(NC4=CC=C(C)C=C4)=O
Molecular Formula
C20H20N2O4S
Molecular Weight
384.45
References & Citations
[1]Koraboina CP et al. Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors. ChemMedChem. 2023 Nov 2:e202300511.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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