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[Ru (dppn) 2phen] (PF6) 2

CAT: 0804-HY-157053Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157053Size:1 Each
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Description
[Ru (dppn) 2phen] (PF6) 2 (compound 4) is a polypyridylruthenium compound used in photodynamic therapy (PDT) . [Ru (dppn) 2phen] (PF6) 2 is normally nontoxic under dark conditions and induces mitochondrial respiratory damage upon light exposure. [Ru (dppn) 2phen] (PF6) 2 exhibits high levels of singlet oxygen quantum yield and phototoxicity against cancer cells[1].
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ru-dppn-2phen-pf6-2.html
Solubility
10 mM in DMSO
Smiles
[F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].C12=CC3=NC4=C(N=C3C=C1C=CC=C2)C5=C6C7=C4C=CC=[N]7[Ru+2]89([N]6=CC=C5)([N]%10=CC=CC%11=C%10C%12=C(C=CC=[N]%129)C%13=C%11N=C%14C=C%15C=CC=CC%15=CC%14=N%13)[N]%16=C%17C(C=CC%18=C%17[N]8=CC=C%18)=CC=C%16
Molecular Formula
C56H32F12N10P2Ru
Molecular Weight
1235.92
References & Citations
[1]Pozza MD et al. Increasing the π-Expansive Ligands in Ruthenium (II) Polypyridyl Complexes: Synthesis, Characterization, and Biological Evaluation for Photodynamic Therapy Applications. Inorg Chem. 2023 Nov 13;62 (45) :18510-18523.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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