[Ru(dppn)2phen](PF6)2

[Ru(dppn)2phen](PF6)2

• UNSPSC Description: [Ru(dppn)2phen](PF6)2 (compound 4) is a polypyridylruthenium compound used in photodynamic therapy (PDT). [Ru(dppn)2phen](PF6)2 is normally nontoxic under dark conditions and induces mitochondrial respiratory damage upon light exposure. [Ru(dppn)2phen](PF6)2 exhibits high levels of singlet oxygen quantum yield and phototoxicity against cancer cells[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/ru-dppn-2phen-pf6-2.html
• Solubility: 10 mM in DMSO
• Smiles: [F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].C12=CC3=NC4=C(N=C3C=C1C=CC=C2)C5=C6C7=C4C=CC=[N]7[Ru+2]89([N]6=CC=C5)([N]%10=CC=CC%11=C%10C%12=C(C=CC=[N]%129)C%13=C%11N=C%14C=C%15C=CC=CC%15=CC%14=N%13)[N]%16=C%17C(C=CC%18=C%17[N]8=CC=C%18)=CC=C%16
• Molecular Weight: 1235.92
• References & Citations: [1]Pozza MD et al. Increasing the π-Expansive Ligands in Ruthenium(II) Polypyridyl Complexes: Synthesis, Characterization, and Biological Evaluation for Photodynamic Therapy Applications. Inorg Chem. 2023 Nov 13;62(45):18510-18523.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported