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MAGL-IN-8

CAT: 0804-HY-157038Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157038Size:1 Each
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Description
MAGL-IN-8 (compound 13) is a reversible monoacylglycerol lipase (MAGL) inhibitor, with an IC50 of 2.5 ± 0.4 nM for hMAGL[1].
CAS Number
3017151-71-9
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/magl-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(O)=C1)N2CCC(CC3=CC=CC(SC4=NC=CC(C(F)(F)F)=C4)=C3)CC2
Molecular Formula
C25H23F3N2O2S
Molecular Weight
472.52
References & Citations
[1]Granchi C, et al. Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. Eur J Med Chem. 2021 Jan 1;209:112857.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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