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BAY-771

CAT: 0804-HY-156965-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156965-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-771, a structurally close pyrimidinedione, is a chemical probe with good lead-like properties and high permeability in Caco-2 cells (no hint of efflux). BAY-771 shows very weak inhibitory activity in the BCAT1 biochemical assay and no activity in BCAT2. BAY-771 can be used as a negative control of HY-148242 BAY-069. BAY-771 can be used for the research of tumor metabolism[1].
CAS Number
2771756-82-0
UNSPSC
12352005
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bay-771.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(F)(F)F)=CC(N1C2=CC(OC3=C(C)C=CC=C3)=CC4=C2C=CC=C4)=O
Molecular Formula
C22H15F3N2O3
Molecular Weight
412.36
References & Citations
[1]Günther J, et al. BAY-069, a Novel (Trifluoromethyl) pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe. J Med Chem. 2022 Nov 10;65 (21) :14366-14390.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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