Cholesterol 24-hydroxylase-IN-2

• UNSPSC Description:

  Cholesterol 24-hydroxylase-IN-2 is an inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), with the IC50 of 5.4 nM. Cholesterol 24-hydroxylase-IN-2 can be used in imaging of cholesterol 24-hydroxylase in mammals[1].

• Target Antigen:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/cholesterol-24-hydroxylase-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1CCN(CC1)C2=C(C3=CC=C(F)C=C3)N=CN=C2)N(C4CC4)C

• Molecular Weight:

  354.42

• References & Citations:

  [1]Koike Tatsuki, et al. Preparation of arylpiperidines and arylpiperazines as radiolabeled compounds for use in imaging of cholesterol 24-hydroxylase. World Intellectual Property Organization, WO2015190613 A1 2015-12-17

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1613481-52-9