Anticancer agent 143

• Description:

  Anticancer agent 143 (compound 369) is a dual PTPN2/PTP1B inhibitor with IC50 values [1].

• UNSPSC:

  12352005

• Target:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-143.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P (O) (C (F) (C1=C (Br) C2=C (C (OCC3=CC=C (S (=O) (C) =O) C=C3) =CC (C4=CN=NN4) =C2) S1) F) O

• Molecular Formula:

  C19H15BrF2N3O6PS2

• Molecular Weight:

  594.34

• References & Citations:

  [1]David A CANDITO, et al. Substituted benzothiophene derivatives and methods of use thereof. Patent WO2023121939A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2948339-38-4