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SARS-CoV-2-IN-65

CAT: 0804-HY-156441Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156441Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SARS-CoV-2-IN-65 (compound 2f (81) ) is a potent, orally active and reversible SARS-CoV-2 entry inhibitor. SARS-CoV-2-IN-65 inhibits the pseudovirus entry in a ACE2-dependent pathway, via mainly inhibiting RBD:ACE2 interaction and TMPRSS2 activity in Calu-3 cells[1].
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-in-65.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC=C(C(/C=C/C3=C4C(NC=C4)=CC=C3)=O)C=C2)CC(C(O)=O)C1
Molecular Formula
C22H18N2O4
Molecular Weight
374.39
References & Citations
[1]Srinivasa Rao Palla, et al. Synthesis, evaluation, and mechanism of 1- (4- (arylethylenylcarbonyl) phenyl) -4-carboxy-2-pyrrolidinones as potent reversible SARS-CoV-2 entry inhibitors. Antiviral Res. 2023 Oct 18:219:105735.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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