SARS-CoV-2-IN-16

SARS-CoV-2-IN-16

• CAS Number: 2761911-40-2
• UNSPSC Description: SARS-CoV-2-IN-16 (Compound 12) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-16 exhibits potent anti-viral activity with the EC50 of 3.69 μM. SARS-CoV-2-IN-16 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-16 is a potent NPro ligand[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-in-16.html
• Solubility: 10 mM in DMSO
• Smiles: NC(C=CC=C12)=C2N(CC)CC3=C1C=C(OC)C(OC)=C3
• Molecular Weight: 284.35
• References & Citations: [1]Yi-Ting Wang, et al. Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2. Eur J Med Chem. 2022 Jan 5;227:113966.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported